Sunday, January 13, 2013

6-Aminonicotinic acid characteristics


6-Aminonicotinic acid is white to ablaze amber powder. It is acclimated as biologic intermediates. solubility in water: 1 g/L ( 20 ℃). The solubility of ethanol: 5 g/L ( 20 ° C ), basically acrid in arctic amoebic solvents. But in booze and acetonitrile in solubility is not actual ideal, but in DMSO solubility can also. Melting point: 300 ℃. Usually on the baptize is not harmful, after government permission, not the actual into the surrounding environment. In accordance with the accoutrement of the use and accumulator are not decomposition. Closed in a air-conditioned dry environment. For blockage of niacin absence ache pellagra. Aswell acclimated as a vasodilator, analysis of hyperlipidemia. Aswell for the analysis of vascular headache, migraine, bookish arterial thrombosis, pulmonary embolism, close ear vertigo, frostbite, axial retinal choroiditis. Strict ascendancy or accept a diet, or accepting parenteral diet patients due to malnutrition, weight loss, pregnancy, lactation, and the use of isoniazid, astringent smoking, alcoholism, biologic addicts, niacin claim of increased.

6-Aminonicotinic acid broadly exists in plants and animals for food, a acceptable antecedent for beastly liver, kidney, angular meat, accomplished grains, beans, milk, blooming abounding vegetables are aswell absolutely content. Nicotinic acerbic in accession to absolute assimilation from food, aswell can be in vivo tryptophan and transformation, an boilerplate of about 60mg tryptophan into 1mg nicotinic acid. The recommended assimilation of developed 12mg/d. Is mainly in the anatomy of coenzyme in foods, are digested in the abdomen and baby civil absorption. After assimilation with nicotinic acerbic in the anatomy of admission to the alarmist via aperture vein. Most of the balance nicotinic acerbic methylation from excreted in urine. The abridgement of advance to the confusion, disorientation, seizures, catatonic schizophrenia, hallucinations, confusion, delirium, and even advance to death. Peripheral neuritis affection such as numbness, afire sensation, beef amore and reflex abnormalities can occur. Sometimes a subacute analgesic after cavalcade collective decline symptoms, may be associated with added vitamin B absence related.

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